Eric L Nuermberger Selected Research

Buruli Ulcer

1/2022	Drug Efficacy Testing in the Mouse Footpad Model of Buruli Ulcer.
10/2021	Impact of Dose, Duration, and Immune Status on Efficacy of Ultrashort Telacebec Regimens in Mouse Models of Buruli Ulcer.
1/2020	Telacebec for Ultrashort Treatment of Buruli Ulcer in a Mouse Model.
1/2019	Shortening Buruli Ulcer Treatment with Combination Therapy Targeting the Respiratory Chain and Exploiting Mycobacterium ulcerans Gene Decay.
1/2019	High-Dose Rifamycins Enable Shorter Oral Treatment in a Murine Model of Mycobacterium ulcerans Disease.
1/2019	Oxazolidinones Can Replace Clarithromycin in Combination with Rifampin in a Mouse Model of Buruli Ulcer.
1/2019	Understanding the Significance of Biochemistry in the Storage, Handling, Purification, and Sampling of Amphiphilic Mycolactone.
1/2018	Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer.
1/2015	Efficacy of Rifampin Plus Clofazimine in a Murine Model of Mycobacterium ulcerans Disease.
1/2014	Accelerated detection of mycolactone production and response to antibiotic treatment in a mouse model of Mycobacterium ulcerans disease.

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Eric L Nuermberger Research Topics

Disease

62	Tuberculosis (Tuberculoses) 01/2022 - 02/2004
29	Infections 01/2022 - 08/2009
16	Buruli Ulcer 01/2022 - 07/2010
12	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 01/2022 - 08/2009
7	Granuloma 04/2016 - 09/2004
6	Pulmonary Tuberculosis 01/2022 - 08/2009
4	Body Weight (Weight, Body) 01/2019 - 07/2012
3	Hypoxia (Hypoxemia) 01/2020 - 03/2009
3	Latent Tuberculosis 01/2017 - 12/2009
3	Necrosis 04/2016 - 06/2015
2	Acquired Immunodeficiency Syndrome (AIDS) 12/2021 - 06/2020
2	Lung Diseases (Lung Disease) 11/2021 - 01/2019
2	Ulcer 01/2019 - 01/2013
1	Communicable Diseases (Infectious Diseases) 01/2022
1	Extensively Drug-Resistant Tuberculosis 11/2021
1	Persistent Infection 01/2021
1	Bacterial Infections (Bacterial Infection) 12/2020
1	Cystic Fibrosis (Mucoviscidosis) 12/2020
1	Nontuberculous Mycobacterium Infections 01/2019
1	Hearing Loss (Hearing Impairment) 01/2015
1	Neglected Diseases 01/2014
1	Skin Diseases (Skin Disease) 10/2011
1	Cicatrix (Scar) 03/2011
1	HIV Infections (HIV Infection) 07/2010
1	Emerging Communicable Diseases (Emerging Infectious Diseases) 07/2010
1	Respiratory Insufficiency (Respiratory Failure) 11/2002
1	Sickle Cell Anemia (Hemoglobin S Disease) 11/2002
1	Sepsis (Septicemia) 11/2002

Drug/Important Bio-Agent (IBA)

40	Pharmaceutical PreparationsIBA 01/2022 - 09/2004
23	Rifampin (Rifampicin)FDA LinkGeneric 01/2022 - 02/2004
20	Isoniazid (Ftivazide)FDA LinkGeneric 01/2022 - 02/2004
20	Pyrazinamide FDA LinkGeneric 01/2022 - 02/2004
15	rifapentine (Priftin)FDA Link 01/2022 - 12/2005
14	Moxifloxacin (Avelox)FDA Link 01/2022 - 02/2004
13	AerosolsIBA 01/2019 - 03/2009
11	bedaquiline (R207910)IBA 01/2022 - 09/2011
11	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 04/2011
11	pretomanidIBA 11/2021 - 01/2011
10	RifamycinsIBA 01/2022 - 07/2006
7	Linezolid (Zyvox)FDA Link 11/2021 - 08/2009
6	FluoroquinolonesIBA 01/2022 - 04/2011
5	Streptomycin (Streptomycin Sulfate)FDA Link 01/2019 - 10/2010
5	Clofazimine (Lamprene)FDA Link 01/2019 - 05/2013
4	VaccinesIBA 01/2020 - 09/2011
4	Ethambutol (Myambutol)FDA LinkGeneric 07/2015 - 08/2012
3	Drug CombinationsIBA 01/2022 - 04/2011
3	LactamsIBA 01/2022 - 01/2019
3	DiarylquinolinesIBA 11/2021 - 01/2021
3	telacebecIBA 10/2021 - 01/2019
3	NitroimidazolesIBA 01/2020 - 01/2011
3	Oxazolidinones (2 Oxazolidone)IBA 01/2019 - 08/2009
2	OPC-67683IBA 01/2022 - 01/2020
2	Meropenem (Merrem)FDA LinkGeneric 01/2022 - 01/2022
2	Antitubercular AgentsIBA 01/2022 - 01/2020
2	Carbapenems (Carbapenem Antibiotics)IBA 01/2022 - 01/2021
2	Imipenem FDA Link 11/2021 - 01/2019
2	ProdrugsIBA 01/2020 - 03/2015
2	Oxidoreductases (Dehydrogenase)IBA 01/2020 - 01/2019
2	mycolactoneIBA 01/2019 - 01/2013
2	AcidsIBA 01/2014 - 10/2012
2	Biomarkers (Surrogate Marker)IBA 01/2012 - 01/2011
1	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 01/2022
1	Rifabutin (Ansamycin)FDA Link 01/2022
1	AcetyltransferasesIBA 12/2021
1	TBAJ-876IBA 11/2021
1	Vitamin K 2 (Vitamin K2)IBA 01/2020
1	Dihydrotachysterol (AT 10)IBA 01/2019
1	Lipoproteins (Lipoprotein)IBA 01/2019
1	Clarithromycin (Biaxin)FDA LinkGeneric 01/2019
1	MacrolidesIBA 01/2019
1	Tigecycline (Tygacil)FDA Link 01/2019
1	relebactamIBA 01/2019
1	meropenem and vaborbactamIBA 01/2019
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2016
1	Matrix Metalloproteinases (MMPs)IBA 01/2016
1	Oxygen (Dioxygen)IBA 03/2015
1	VXc-486IBA 03/2015
1	TBA-354IBA 01/2015
1	Levofloxacin (Levaquin)FDA Link 07/2013
1	beta-LactamsIBA 05/2013
1	trichostatin A (A 300)IBA 11/2012
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2012
1	CarbonIBA 10/2012
1	NitrogenIBA 10/2012
1	pimonidazoleIBA 02/2012
1	7- (7- amino- 7- methyl- 5- azaspiro(2.4)heptan- 5- yl)- 6- fluoro- 1- (2- fluoro- 1- cyclopropyl)- 1,4- dihydro- 8- methoxy- 4- oxo- 3- quinolinecarboxylic acidIBA 04/2011
1	CytokinesIBA 03/2011
1	Glucose (Dextrose)FDA LinkGeneric 11/2009
1	PNU-100480IBA 08/2009
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2009
1	Dioctyl Sulfosuccinic Acid (DOSS)IBA 03/2009
1	Interferon-gamma (Interferon, gamma)IBA 09/2004

Therapy/Procedure

10	Duration of Therapy 01/2022 - 02/2004
7	Therapeutics 01/2019 - 11/2002
7	Drug Therapy (Chemotherapy) 01/2017 - 02/2004
3	Skin Transplantation (Skin Grafting) 01/2022 - 10/2011
2	Aftercare (After-Treatment) 01/2016 - 01/2013
2	Intramuscular Injections 01/2015 - 10/2010
1	Salvage Therapy 01/2019
1	Combination Drug Therapy (Combination Chemotherapy) 07/2010